The situation has been broadly well identified that genes do not perform unaided; rather sets of genes act in acquaintance during a genetic process. Subsequently, the expression levels of genes need each other.Experimental procedures to perceive such interacting pairs of genes have been in place for fairly several times. Through the introduction of microarray technology, fresher computational techniques to differentiate such interaction or relationship between genes expressions are being projected which leads to an association network. Nevertheless most microarray analyses the appearance of genes that are differentially expressed, it is of cautiously greater significance to identify how all-inclusive association network structures change between two or more biological environs, approximately normal against diseased cell types.